SELECT 
  product_prices.product_id, 
  MIN(
    IF(
      product_prices.percentage_discount = 0, 
      product_prices.price, 
      product_prices.price - (
        product_prices.price * product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  product_prices 
WHERE 
  product_prices.product_id IN (
    279255, 279262, 279250, 283189, 283181, 
    287067, 283182, 287105, 287107, 279258, 
    287108, 287106, 287059, 287111, 287102, 
    283188, 287104, 287068
  ) 
  AND product_prices.lower_limit = 1 
  AND product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  product_prices.product_id

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "15.66"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 18,
        "rows_produced_per_join": 1,
        "filtered": "10.00",
        "index_condition": "(`goimagine`.`product_prices`.`product_id` in (279255,279262,279250,283189,283181,287067,283182,287105,287107,279258,287108,287106,287059,287111,287102,283188,287104,287068))",
        "cost_info": {
          "read_cost": "15.48",
          "eval_cost": "0.18",
          "prefix_cost": "15.66",
          "data_read_per_join": "43"
        },
        "used_columns": [
          "id",
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`goimagine`.`product_prices`.`lower_limit` = 1) and (`goimagine`.`product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}

Result

product_id price
279250 35.00000000
279255 35.00000000
279258 35.00000000
279262 35.00000000
283181 35.00000000
283182 40.00000000
283188 25.00000000
283189 25.00000000
287059 35.00000000
287067 35.00000000
287068 25.00000000
287102 45.00000000
287104 45.00000000
287105 45.00000000
287106 45.00000000
287107 40.00000000
287108 40.00000000
287111 40.00000000