Sandbox

SELECT 
  b.variant_name, 
  a.* 
FROM 
  product_option_variants AS a 
  LEFT JOIN product_option_variants_descriptions AS b ON b.variant_id = a.variant_id 
  AND b.lang_code = 'en' 
WHERE 
  1 
  AND a.option_id IN (
    21222, 21225, 21224, 21389, 21254, 21256, 
    21460
  ) 
  AND a.status = 'A' 
ORDER BY 
  a.position, 
  a.variant_id

Query time 0.00112

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "151.61"
    },
    "ordering_operation": {
      "using_filesort": true,
      "cost_info": {
        "sort_cost": "53.00"
      },
      "nested_loop": [
        {
          "table": {
            "table_name": "a",
            "access_type": "range",
            "possible_keys": [
              "status",
              "option_id",
              "option_id_2"
            ],
            "key": "option_id",
            "used_key_parts": [
              "option_id",
              "status"
            ],
            "key_length": "6",
            "rows_examined_per_scan": 53,
            "rows_produced_per_join": 53,
            "filtered": "100.00",
            "index_condition": "((`goimagine`.`a`.`option_id` in (21222,21225,21224,21389,21254,21256,21460)) and (`goimagine`.`a`.`status` = 'A'))",
            "cost_info": {
              "read_cost": "47.53",
              "eval_cost": "5.30",
              "prefix_cost": "52.83",
              "data_read_per_join": "2K"
            },
            "used_columns": [
              "variant_id",
              "option_id",
              "position",
              "modifier",
              "modifier_type",
              "weight_modifier",
              "weight_modifier_type",
              "point_modifier",
              "point_modifier_type",
              "status",
              "etsy_variant_id"
            ]
          }
        },
        {
          "table": {
            "table_name": "b",
            "access_type": "eq_ref",
            "possible_keys": [
              "PRIMARY"
            ],
            "key": "PRIMARY",
            "used_key_parts": [
              "variant_id",
              "lang_code"
            ],
            "key_length": "9",
            "ref": [
              "goimagine.a.variant_id",
              "const"
            ],
            "rows_examined_per_scan": 1,
            "rows_produced_per_join": 53,
            "filtered": "100.00",
            "cost_info": {
              "read_cost": "40.48",
              "eval_cost": "5.30",
              "prefix_cost": "98.61",
              "data_read_per_join": "40K"
            },
            "used_columns": [
              "variant_id",
              "lang_code",
              "variant_name"
            ]
          }
        }
      ]
    }
  }
}

Result

variant_name	variant_id	option_id	position	modifier	modifier_type	weight_modifier_type	point_modifier_type	status
Nickel	83405	21222	0	0.000	A	A	A	A
Gold	83406	21222	0	0.000	A	A	A	A
Keychain	83450	21224	0	0.000	A	A	A	A
Sausage Chain	83451	21224	0	0.000	A	A	A	A
Military Chain	83452	21224	0	0.000	A	A	A	A
3-3/4x3-3/4"	84560	21460	0	0.000	A	A	A	A
6x6"	84561	21460	0	8.000	A	A	A	A
Arial	83586	21254	1	0.000	A	A	A	A
Aurora	83638	21254	2	0.000	A	A	A	A
Bank Gothic	83588	21254	3	0.000	A	A	A	A
Beauford	83589	21254	4	0.000	A	A	A	A
Berlin Sans	83590	21254	5	0.000	A	A	A	A
Bernard	83591	21254	6	0.000	A	A	A	A
Berry Juice	83592	21254	7	0.000	A	A	A	A
Blueberry	83593	21254	8	0.000	A	A	A	A
Brush Script	83594	21254	9	0.000	A	A	A	A
Californian	83595	21254	10	0.000	A	A	A	A
Calligraph	83596	21254	11	0.000	A	A	A	A
Century Gothic	83597	21254	12	0.000	A	A	A	A
Cocktail Shaker	83598	21254	13	0.000	A	A	A	A
Comic Sans	83639	21254	14	0.000	A	A	A	A
Cooper	83600	21254	15	0.000	A	A	A	A
Copperplate Gothic	83601	21254	16	0.000	A	A	A	A
Eras Demi	83602	21254	17	0.000	A	A	A	A
Excelsior	83603	21254	18	0.000	A	A	A	A
Felix Titling	83604	21254	19	0.000	A	A	A	A
Forte	83605	21254	20	0.000	A	A	A	A
Freehand	83606	21254	21	0.000	A	A	A	A
Gunship	83607	21254	22	0.000	A	A	A	A
Harrington	83608	21254	23	0.000	A	A	A	A
Headster	83609	21254	24	0.000	A	A	A	A
Hobo	83610	21254	25	0.000	A	A	A	A
Impact	83611	21254	26	0.000	A	A	A	A
Kids	83634	21254	27	0.000	A	A	A	A
Magenta	83635	21254	28	0.000	A	A	A	A
Monotype Corsiva	83636	21254	29	0.000	A	A	A	A
Noteworthy	83637	21254	30	0.000	A	A	A	A
Old English	83616	21254	31	0.000	A	A	A	A
Old School	83617	21254	32	0.000	A	A	A	A
Papyrus	83618	21254	33	0.000	A	A	A	A
Righteous	83619	21254	34	0.000	A	A	A	A
Rock Salt	83620	21254	35	0.000	A	A	A	A
Signature	83621	21254	36	0.000	A	A	A	A
Stencil	83622	21254	37	0.000	A	A	A	A
Tahoma	83623	21254	38	0.000	A	A	A	A
Throw my hands up	83624	21254	39	0.000	A	A	A	A
Times New Roman	83625	21254	40	0.000	A	A	A	A
Tiranti Solid	83626	21254	41	0.000	A	A	A	A
Wide Latin	83627	21254	42	0.000	A	A	A	A
Winchester	83628	21254	43	0.000	A	A	A	A